Emma Fernández-Repollet, Ph.D.
ONGOING
G12 MD0007600 Emma Fernández-Repollet (PI)
2011- 2016
NIH NIMHD
Center for Collaborative Research in Health Disparities
The goal of the Center for Collaborative Research in Health Disparities for 2011-2016 is to develop a more efficient and competitive research infrastructure at the University of Puerto Rico Medical Sciences Campus (UPR-MSC) to conduct translational studies in health disparities affecting the Puerto Rican population.
Role: PI
U54 MD022762 Elizabeth Ofili (PI)
2012 – 2017
NIH NIMHD
RCMI Translational Research Network (RTRN)
The RCMI Translational Research Network (RTRN) is a consortium comprising of 1) basic, clinical and translational investigators from the RCMI institutions, and 2) investigators from non-RCMI academic health centers, community organizations, and other relevant organizations which are linked via a robust information technology infrastructure. RTRN enables these institutions to pool their resources and expertise to conduct high-quality, collaborative, multi-center clinical and translational research resulting in an increase in the productivity and impact of each of the individual centers, with the ultimate goal of fostering improved health outcomes and eliminating racial and ethnic disparities in health.
Role: Steering Committee, Chair
COMPLETED
U54 RR022762 K. Norris (PI)
2007 – 2012
NIH NCRR
RCMI Translational Research Network (RTRN)
The RCMI Translational Research Network (RTRN) is a consortium comprising of 1) basic, clinical and translational investigators from the RCMI institutions, and 2) investigators from non-RCMI academic health centers, community organizations, and other relevant organizations which are linked via a robust information technology infrastructure. RTRN enables these institutions to pool their resources and expertise to conduct high-quality, collaborative, multi-center clinical and translational research resulting in an increase in the productivity and impact of each of the individual centers, with the ultimate goal of fostering improved health outcomes and eliminating racial and ethnic disparities in health.
Role: Steering Committee, Chair
U24 RR029825 Lee Nadler (PI)
2009 - 2012
NIH NCRR
Networking Research Resources Across America
Nine-member consortium from across the country to create a National Research Resource Discovery (NRRD) network. The goal of this award is to enable biomedical scientists from anywhere in the US to search resource inventories at all nine participating sites and request access to resources that will assist in their work. The network will be built such that resource inventories from additional sites can be added over time.
Role: Sub-Recipient PI
G12 RR03051 Rafael Rodriguez-Mercado (PI)
2006-2011
NIH NCRR RCMI
Health Disparities Research Program
The overall goal of this program is to enhance the biomedical research capabilities of the University of Puerto Rico Medical Sciences Campus. This goal is being achieved by developing infrastructure and support services which facilitate the conduct of research; targeting specific areas of research for further development, especially those that promote basic and clinical collaborations; and developing the research potential of current and newly recruited faculty. The current funding cycle focuses on developing and enhancing research capability to conduct studies addressing health conditions that disproportionately affect the Puerto Rican population. The project has also established the administrative structure necessary to carry out program goals and oversee those facilities which provide research services.
Role: Program Director
U24 RR029825 Lee Nadler (PI)
2009 – 2011
NIH NCRR
Networking Research Resources Across America
Nine-member consortium from across the country to create a National Research Resource Discovery (NRRD) network. The goal of this award is to enable biomedical scientists from anywhere in the US to search resource inventories at all nine participating sites and request access to resources that will assist in their work. The network will be built such that resource inventories from additional sites can be added over time.
Role: Sub-Recipient PI
G12 RR03051 José R. Carlo (PI)
2001-2006
NIH NCRR RCMI
Health Disparities Research Program
The overall goal of this program is to enhance the biomedical research capabilities of the University of Puerto Rico Medical Sciences Campus. This goal is being achieved by developing infrastructure and support services which facilitate the conduct of research; targeting specific areas of research for further development, especially those that promote basic and clinical collaborations; and developing the research potential of current and newly recruited faculty. The current funding cycle focuses on developing and enhancing research capability to conduct studies addressing health conditions that disproportionately affect the Puerto Rican population. The project has also established the administrative structure necessary to carry out program goals and oversee those facilities which provide research services.
Role: Program Director
R25 RR07415 Emma Fernández-Repollet (PI)
2003- 2008
NIH NCRR SEPA
Puerto Rico Biomedical Research Education Program (PR-BREP)
The main goal of the PR-BREP proposed by the University of Puerto Rico Medical Sciences Campus, is to improve the knowledge of K-12 Puerto Rican children about biomedical research focusing on diseases and disorders that disproportionately impact our population. This should increase the number of students who pursue graduate degrees in the biomedical sciences. To achieve this goal we propose to develop following five initiatives: Student Enrichment Program, Professional Development Program, Summer Internship Program, Mini-Grants Award Program, Community Outreach Program.
Special emphasis will be given to topics such as: diabetes, diseases of the heart, cancer, hypertension, obesity, AIDS, and cerebrovascular diseases, which are closely related with the leading causes of death in Puerto Rico and other Hispanic/Latino groups.
G12 RR03051 Jorge Sánchez, Adolfo Firpo (PI)
1996-2001
NIH NCRR RCMI
RCMI Research Program
The overall goal of this program was to enhance the biomedical research capabilities of the University of Puerto Rico Medical Sciences Campus. This goal was achieved by developing infrastructure and support services which facilitated the conduct of research; targeting specific areas of research for further development, especially those that promote basic and clinical collaborations; and developing the research potential of current and newly recruited faculty.
Role: Program Director
G12 RR003051 Emma Fernández-Repollet (PI)
1999-2001
NIH NCRR
Quantification of CD95 Expression in Puerto Rican Children with Type 1 Diabetes Mellitus
This project focused on the role of T cells in type 1 diabetes mellitus. The main objective was to quantify the expression of Fas (CD95/APO-1) and Fas ligand molecule (FasL) on peripheral blood lymphocytes obtained from Puerto Rican children newly diagnosed with type 1 diabetes and subjects at high risk of developing the disease. It also examined whether decreased susceptibility of lymphocytes to Fas and Fas L induced apoptosis can be used as an immunological marker of type 1 diabetes pathogenesis in vivo.
GRS-5-S06-GM-8224 Jean Turnquist/ Emma Fernández-Repollet (PI)
1996-2000
NIH NIGM MBRS
Role of Mesangial Cells in Diabetes Mellitus
The major goal of this project was to assess the role of mesangial cell function in early diabetes by establishing an in vitro mesangial cell culture derived from streptozotocin-treated rats. The project also evaluated whether the enhanced proliferative response of “diabetic” mesangial cells was associated with an impaired response to stimulatory and/or inhibitory mitogenic factors. The role of alterations in intracellular calcium concentration in normal and “diabetic” mesangial cells in response to angiotensin II and vasopressin and its correlation with changes in the contractile response to these agents was also examined.
